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1.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery ; (12): 354-359, 2023.
Article in Chinese | WPRIM | ID: wpr-982748

ABSTRACT

Objective:To analyze the risk factors of recurrence and canceration for premalignant vocal fold lesions after surgery, and to provide a reasonable basis for preoperative evaluation and postoperative follow-up. Methods:This study retrospective analyzed the relationship between clinicopathological factors and clinical outcome(recurrence, canceration, recurrence-free survival, and canceration-free survival) in 148 patients undergoing surgical treatment in Chongqing General Hospital from 2014 to 2017. Results:The five-year overall recurrence rate was 14.86% and the overall recurrence rate was 8.78%. Univariate analysis showed that smoking index, laryngopharyngeal reflux and lesion range were significantly associated with recurrence(P<0.05), and smoking index and lesion range were significantly associated with canceration(P<0.05). Multivariate logistic regression analysis showed that smoking index ≥600 and laryngopharyngeal reflux were independent risk factors for recurrence(P<0.05), and smoking index ≥600 and lesion range ≥1/2 vocal cord were independent risk factors for canceration(P<0.05). The mean carcinogenesis interval for the postoperative smoking cessation group was significantly longer(P<0.05). Conclusion:Excessive smoking, laryngopharyngeal reflux and a wide range of lesions may be related to postoperative recurrence or malignant progression of precancerous lesions in the vocal cord, and further large-scale multi-center prospective randomized controlled studies are needed to clarify the effects of the above factors on recurrence and malignant changes in the future.


Subject(s)
Humans , Vocal Cords/pathology , Retrospective Studies , Laryngopharyngeal Reflux/complications , Prospective Studies , Precancerous Conditions/pathology , Risk Factors
2.
Braz. j. otorhinolaryngol. (Impr.) ; 87(2): 200-204, mar.-abr. 2021. tab
Article in English, Portuguese | LILACS | ID: biblio-1249358

ABSTRACT

Resumo Introdução: Muitos problemas relacionados à laringe têm sido atribuídos ao refluxo laringofaríngeo, inclusive disfonia, pigarro frequente, tosse crônica e sensação de "globus" faríngeo. No entanto, ainda há controvérsias quanto ao diagnóstico e à apresentação clínica dessa condição clínica. Objetivo: Descrever as características do refluxo laringofaríngeo de diferentes posições, em pacientes diagnosticados por meio de pHmetria orofaríngea. Método: Foi feita uma revisão retrospectiva de prontuários de 161 pacientes com refluxo laringofaríngeo diagnosticado por pHmetria orofaríngea de 24 horas. Os indivíduos do estudo foram categorizados em grupos com refluxo laringofaríngeo na posição ortostática e refluxo laringofaríngeo na posição supina com base nos resultados do pH. Os dois grupos foram comparados quanto à apresentação clínica e às características do pH. Resultados: Foram encontradas taxas significativamente mais altas de refluxo laringofaríngeo na posição ortostática em comparação à posição supina (p < 0,0001). Os resultados do índice de sintomas de refluxo foram significativamente maiores no grupo com refluxo laringofaríngeo na posição ortostática em comparação com o grupo com refluxo laringofaríngeo na posição supina. O uso do escore de Ryan composto (composite Ryan score) para a pHmetria orofaríngea de 24 horas foi significantemente maior no grupo com refluxo laringofaríngeo ortostático em relação ao grupo supino (p < 0,0001). Nenhuma diferença significante foi encontrada entre os grupos refluxo laringofaríngeo na posição ortostática e posição supina em relação à frequência da apresentação clínica ou classificações do índice de desvantagem vocal. Conclusão: O refluxo laringofaríngeo foi mais prevalente na posição ortostática entre os grupos de estudo. As características relacionadas ao refluxo, inclusive parâmetros de pH, foram mais evidentes no refluxo laringofaríngeo na posição ortostática.


Subject(s)
Humans , Dysphonia , Laryngopharyngeal Reflux/complications , Laryngopharyngeal Reflux/diagnosis , Pharynx , Retrospective Studies , Hydrogen-Ion Concentration
3.
CoDAS ; 32(5): e20180052, 2020. tab, graf
Article in Portuguese | LILACS | ID: biblio-1133536

ABSTRACT

RESUMO Objetivo: Verificar a associação entre Refluxo laringofaríngeo (RLF) com idade, sexo, desvio vocal e queixas de voz. Método: Participaram do estudo pacientes entre 18 e 70 anos, encaminhados ao serviço de otorrinolaringologia por queixas de voz ou refluxo, de ambos os sexos. Os achados endolaríngeos foram classificados utilizando a escala Reflux Finding Score (RFS). A presença ou não de queixas vocais e de refluxo foi verificada e correlacionada com a classificação RFS. Na mesma data, os pacientes foram submetidos à gravação de voz de vogal sustentada e fala encadeada. A avaliação perceptivo-auditiva foi realizada por uma fonoaudióloga, classificando o grau geral do desvio vocal com base na escala GRBASI. Resultados: Foram avaliados 97 pacientes, com média de idade de 42,6 anos, sendo 62,3% do sexo feminino e média dos escores da escala RFS igual a 6,26 pontos. Do total de pacientes, 48 indivíduos apresentavam queixas vocais, sendo 34 mulheres com idade média de 44,9 anos e escore RFS médio de 6,94 pontos. Os outros 49 indivíduos não apresentavam queixas vocais, e desses 27 eram mulheres, com idade média de 41,2 anos e média de escore RFS igual a 5,5 pontos. As variáveis "queixa de refluxo", "queixa vocal" e idade foram as que mais se correlacionaram com os escores da escala RFS. Conclusão: Há relação entre queixas de refluxo, achados laríngeos e queixa vocal.


ABSTRACT Purpose: To verify the association between laryngopharyngeal reflux (LPR) with age, gender, vocal deviation and voice complaints. Methods: The study included patients between 18 and 70 years old, referred to the Otorhinolaryngology service for complaints of voice or reflux, of both sexes. Endolaryngeal findings were classified using the Reflux Finding Score (RFS) scale. The presence or absence of vocal and reflux complaints was verified and correlated with the RFS classification. On the same date, they were submitted to sustained vowel voice recording and chained speech. The auditory-perceptual assessment was performed by a speech therapist, classifying the general degree of vocal deviation based on the GRBASI scale. Results: Ninety-seven patients were evaluated, with a mean age of 42. 6 years, 62. 3% female, and mean RFS scores of 6. 26 points. Among the patients, 48 subjects had vocal complaints, 34 women with a mean age of 44. 9 years and an average RFS score of 6. 94 points. The other 49 individuals had no vocal complaints, and of these 27 were women, with a mean age of 41. 2 years and a mean RFS score of 5. 5 points. The variables "reflux complaint", "vocal complaint" and age were the ones that most correlated with the RFS scale scores. Conclusion: There is a relationship among reflux complaints, laryngeal findings and vocal complaint.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Aged , Young Adult , Voice , Laryngopharyngeal Reflux/complications , Laryngopharyngeal Reflux/diagnosis , Voice Quality , Middle Aged
4.
Int. arch. otorhinolaryngol. (Impr.) ; 23(3): 322-324, July-Sept. 2019. tab, graf
Article in English | LILACS | ID: biblio-1040027

ABSTRACT

Abstract Introduction Laryngeal granulomas are benign, recurrent lesions of many causes (reflux, voice abuse, intubation, and idiopathic), which renders its treatment difficult. Objective To describe our experience in the treatment of laryngeal granulomas. Methods From 16 medical records of the patients with laryngeal granulomas seen between 2010 and 2017 in a university hospital, the following data were analyzed: age, gender, vocal and gastroesophageal symptoms, vocal overuse, intubation, treatments, videolaryngoscopy before and after the treatment. Results Gender: female, 10; male, 6. Age: between 20 and 60 years old (11%). Etiology of the granulomas: intubation (9), reflux (4), idiopathic (3). The initial treatments adopted in all cases were: inhaled beclomethasone dipropionate 100 μg 12/12 hours (1month), proton pump inhibitor, omeprazole 40 mg/day (2months), and dietary and voice education. After this period, 10 patients (7 postintubation, 3 idiopathic) were submitted to surgery, since no improvements in the symptoms or in the lesions were seen. Of these, two recurred, requiring a second surgery, one of which recurred six times and received botulinum toxin A. Only one patient with granulomas due to laryngopharyngeal reflux presented no improvement in the symptoms nor in the lesion after the pharmacological treatment and had been submitted to microsurgery. All of the other patients with reflux granulomas were successfully treated with the drug treatment, and the longest treatment time for complete remission of the symptoms and of the lesions was 9 months. Conclusions In laryngeal granulomas caused by reflux, treatment with inhaled steroids and proton pump inhibitors proved to be effective, although prolonged. In postintubation and idiopathic granulomas, surgery was the best treatment.


Subject(s)
Humans , Male , Female , Child , Adult , Middle Aged , Granuloma, Laryngeal/therapy , Granuloma, Laryngeal/surgery , Granuloma, Laryngeal/complications , Granuloma, Laryngeal/etiology , Granuloma, Laryngeal/drug therapy , Medical Records , Proton Pump Inhibitors/therapeutic use , Laryngopharyngeal Reflux/complications , Intubation/adverse effects , Microsurgery
5.
Braz. j. otorhinolaryngol. (Impr.) ; 85(4): 408-415, July-Aug. 2019. tab, graf
Article in English | LILACS | ID: biblio-1019588

ABSTRACT

Abstract Introduction Obstructive sleep apnea syndrome and laryngopharyngeal reflux are diseases with a high prevalence in the overall population; however, it remains unclear whether they are diseases with the same risk factors present in the same populations or if there is any association between them. Objectives To evaluate and determine the prevalence of laryngopharyngeal reflux in patients with moderate and severe obstructive apnea syndrome and also to determine its predictive factors. Methods Historical cohort, cross-sectional study of patients aged 18-70 years, referred to a tertiary service Otorhinolaryngology outpatient clinic with a polysomnographic diagnosis of moderate or severe obstructive sleep apnea syndrome. The reflux symptom index questionnaire and the reflux finding score at indirect videolaryngoscopy were applied to the assessed population, considering the inclusion and exclusion criteria. Results Fifty-six patients were evaluated, of which 64.3% had a positive laryngopharyngeal reflux (positive reflux symptom index and/or positive endolaryngeal reflux finding score). Body mass index was a predictor of reflux presence in this group of patients with moderate to severe obstructive sleep apnea syndrome. In patients with positive score for endoscopic findings and reflux symptom index (12.3%), there was a trend toward significance for a higher mean apnea-hypopnea index and a higher percentage of sleep time with oxyhemoglobin saturation below 90% (p = 0.05). Conclusion The prevalence of laryngopharyngeal reflux was higher in this group of patients with moderate to severe obstructive sleep apnea syndrome, and the body mass index was a predictor of laryngopharyngeal reflux in these patients. There was a trend toward greater oxyhemoglobin desaturation in patients with a positive score for reflux symptoms index (RSI) and reflux finding score (RFS).


Resumo Introdução A síndrome da apneia obstrutiva do sono e o refluxo laringofaríngeo são doenças com alta prevalência na população em geral. No entanto, ainda não está claro se são doenças com os mesmos fatores de risco presentes nas mesmas populações ou se há alguma relação entre elas. Objetivo Avaliar e determinar a prevalência de refluxo laringofaríngeo em pacientes com síndrome da apneia obstrutiva moderada e acentuada, bem como determinar os fatores preditivos de refluxo nesses pacientes. Método Estudo de coorte histórica com corte transversal de pacientes entre 18 e 70 anos, encaminhados a um ambulatório de Otorrinolaringologia em serviço terciário, com diagnóstico polissonográfico de síndrome da apneia obstrutiva do sono moderada ou acentuada. Foram aplicados o questionário Reflux Sympton Index e o escore de achados endolaríngeos por meio de videolaringoscopia indireta na população estudada, respeitando os critérios de inclusão e exclusão. Resultados Foram avaliados 56 pacientes, dos quais 64,3% apresentaram refluxo laringofaríngeo (Reflux Sympton Index positivo e/ou Reflux Finding Score positivo). O índice de massa corpórea foi fator preditor da presença de refluxo laringofaríngeo nesse grupo de pacientes com síndrome da apneia obstrutiva do sono moderada e acentuada. Nos pacientes cujos Reflux Sympton Index e o escore de achados endolaríngeos foram positivos (12,3%), houve uma tendência à significância para maior índice de apneia e hipopneia e maior porcentagem do tempo de sono com saturação de oxi-hemoglobina abaixo de 90% (p = 0,05). Conclusão A prevalência de refluxo laringofaríngeo foi alta nesse grupo de pacientes com síndrome da apneia obstrutiva do sono moderada e acentuada e o índice de massa corpórea foi fator preditor de refluxo nesses pacientes. Houve uma tendência a maior dessaturacão de oxi-hemoglobina em pacientes com "índice de sintomas de refluxo" e escore de achados endolaríngeos positivos.


Subject(s)
Humans , Male , Female , Adult , Aged , Sleep Apnea, Obstructive/complications , Laryngopharyngeal Reflux/complications , Severity of Illness Index , Brazil , Body Mass Index , Cross-Sectional Studies , Surveys and Questionnaires , Polysomnography , Sleep Apnea, Obstructive/diagnosis , Laryngopharyngeal Reflux/diagnosis
8.
Rev. otorrinolaringol. cir. cabeza cuello ; 77(4): 456-466, dic. 2017. tab
Article in Spanish | LILACS | ID: biblio-902803

ABSTRACT

La tos ocurre por la compleja acción del arco de la tos. En condiciones normales es esencial para proteger la vía aérea. Es un síntoma muy frecuente, con un gran número de etiologías posibles. El enfrentamiento diagnóstico de los pacientes con tos crónica, puede resultar un desafío diagnóstico. Deben considerarse las patologías más prevalentes, que incluyen el reflujo faringolaríngeo y la descarga posterior: ambas condiciones que son parte del área otorrinolaringológica. En el presente artículo de revisión se pretende entregar un enfoque actualizado de su enfrentamiento y manejo, con la finalidad de aportar información que resulte relevante para la práctica clínica diaria.


Cough occurs due to the complex action of the coughing arch. Under normal conditions it is essential to protect the airway. It is a very frequent symptom with a large of possible etiologies. The diagnosis process of patients with chronic cough can be a challenge. The most prevalent pathologies must be considered. Thus includes pharyngolaryngeal reflux and posterior discharge: both conditions that are part of the otorhinolaryngolocical area. In the present article review, we pretend to provide an updated approach and management to this condition, in order to asses relevant information to daily clinical practice.


Subject(s)
Humans , Cough/diagnosis , Cough/etiology , Otolaryngology , Chronic Disease , Cough/physiopathology , Cough/therapy , Laryngopharyngeal Reflux/complications
9.
Arch. endocrinol. metab. (Online) ; 61(4): 348-353, July-Aug. 2017. tab, graf
Article in English | LILACS | ID: biblio-887582

ABSTRACT

ABSTRACT Objective This study aims to compare the prevalence of laryngopharyngeal reflux signs between two groups of patients undergoing thyroidectomy for voluminous goiter: substernal goiters and voluminous cervical goiter without thoracic extension. Subjects and methods A retrospective case-control study was performed with data retrieved of the charts of the patients submitted to thyroidectomies occurred at a tertiary care center (Head and Neck Surgery Department, University of São Paulo Medical School) between 2010 and 2014. The selected thyroidectomies were allocated in two groups for study: patients with substernal goiters and patients with voluminous cervical goiter without thoracic extension. Cervical goiters were selected by ultrasonography mensuration. Clinical criterion was used to define substernal goiter. Results The average thyroid volume in patients with substernal goiter was significantly greater than the average volume in patients with only cervical goiter (p < 0.001). The prevalence of signs of reflux laryngitis at laryngoscopy was significantly greater in substernal goiter patients (p = 0.036). Moreover, substernal goiter was considered as the unique independent variable for high reflux laryngitis signs at laryngoscopy (OR = 2.75; CI95%: 1.05-7.20; p = 0.039) when compared to only cervical goiter patients. Conclusion This study shows a significant association between substernal goiters and signs of laryngopharyngeal reflux at preoperative laryngoscopy. Therefore, when compared with voluminous cervical goiters, the substernal goiters increase the chance of reflux laryngitis signs in patients.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Laryngopharyngeal Reflux/epidemiology , Goiter, Substernal/epidemiology , Thyroidectomy , Case-Control Studies , Prevalence , Retrospective Studies , Laryngopharyngeal Reflux/complications , Laryngopharyngeal Reflux/diagnostic imaging , Goiter/surgery , Goiter/complications , Goiter/physiopathology , Goiter/epidemiology , Goiter, Substernal/surgery , Goiter, Substernal/complications , Goiter, Substernal/physiopathology , Laryngoscopy
10.
CoDAS ; 28(3): 302-310, tab
Article in Portuguese | LILACS | ID: lil-788069

ABSTRACT

RESUMO Objetivo Analisar a relação entre a presença de sinais videolaringoscópicos sugestivos de refluxo laringofaríngeo (RLF) e distúrbio de voz (DV) em professoras. Métodos Pesquisa de natureza transversal, com amostra por conveniência que teve, como critérios de inclusão, ter mais de 18 anos, ser professor do sexo feminino, procurar atendimento com queixa de DV e/ou de RLF. Os fatores de exclusão foram: ser fumante e apresentar alterações respiratórias. Todos os sujeitos preencheram os seguintes instrumentos: Condição de Produção Vocal – Professor (CPV-P), inclusive o Índice de Triagem para Distúrbio de Voz (ITDV), e o Índice de Desvantagem Vocal (IDV). Fez-se coleta de amostra de fala para avaliação perceptivo-auditiva da voz e todas foram submetidas à avaliação otorrinolaringológica. Resultados Foram avaliadas 121 professoras, com média de idade de 43 anos e de 7,8 horas-aula por dia. Somente 24% das professoras não apresentaram lesões em pregas vocais e 42,1% apresentaram sinais videolaringoscópicos sugestivos de RLF. No grupo de professoras com presença de sinais de RLF, os sintomas do ITDV mais relatados foram garganta seca, rouquidão, pigarro, e a média do IDV foi de 17,9 pontos. Não houve associação entre distúrbio de voz e presença de sinais videolaringoscópicos sugestivos de RLF. Na análise de regressão logística binária múltipla, os fatores independentes para o RLF foram idade e escore (tercil: 13-20) do IDV. Conclusão Não houve associação entre o DV e o RLF e sim entre idade e escore IDV.


ABSTRACT Objective To analyze the relationship between the presence of videolaryngoscopic signs suggestive of laryngopharyngeal reflux (LPR) and voice disorder (VD) in teachers. Methods this is a cross-sectional study with convenience sample and inclusion criteria as subjects 18 years or older, be a teacher female, seek care with complaint of VD and/or LPR. The exclusion criteria included smoking and presence of respiratory changes. All subjects concluded the following instruments: Vocal Production Condition - Teacher (VPC-T), including the Screening Index for Voice Disorder (SIVD); and Voice Handicap Index (VHI). Speech samples were collected for voice perceptual assessment and all of them were submitted to otorhinolaryngology review. Results We evaluated 121 teachers, with a mean age of 43 years and 7.8 class hours per day. Only 24.0% of the teachers did not have vocal cord lesions and 42.1% had videolaryngoscopic signs suggestive of LPR. In the group of teachers with presence of Signs suggestive of LPR, the most common symptoms of SIVD were dry throat, hoarseness, throat clearing; the average VHI was 17.9 points. There was no association between voice disorder and presence of videolaryngoscopic signs suggestive of LPR. The independent factors for the LPR in the multiple binary logistic regression analysis were age and VHI score (tertile: 13-20). Conclusion There was no association between VD and LPR, but between age and VHI score.


Subject(s)
Humans , Female , Adult , Young Adult , Voice Disorders/diagnostic imaging , Laryngopharyngeal Reflux/diagnostic imaging , School Teachers , Voice Quality/physiology , Voice Disorders/complications , Hoarseness/etiology , Cross-Sectional Studies , Surveys and Questionnaires , Age Factors , Stroboscopy , Laryngopharyngeal Reflux/complications , Laryngoscopy , Middle Aged
11.
Rio de Janeiro; s.n; 2016. 53 p. ilus, tab.
Thesis in Portuguese | LILACS, BBO | ID: biblio-1099518

ABSTRACT

Este estudo teve como objetivo comparar pacientes submetidos a cirurgia bariátrica com e sem tratamento bucal. A metodologia utilizada foi de questionários com dados gerais do paciente (anamnese e exame clínico), questionário de autopercepção da saúde bucal dos pacientes (OHIP-14), questionário de hábitos alimentares, testes salivares, índice para erosão dentária (BEWE) e índices periodontais. O resultado mostrou que os grupos tratados pelo cirurgião-dentista apresentaram ganhos como: em autopercepção da saúde bucal (questionário OHIP-14), em melhora dos problemas periodontais e confirmaram uma diminuição de pH e aumento de frequência de vômitos em pacientes pós cirúrgicos. Assim, baseados nos achados desta pesquisa, conclui-se que a Doença do Refluxo Gástrico Esofágico (DRGE), é um fator de risco, também, nos bariátricos. Foi realizado estudo experimental, controlado, não randomizado, com um acompanhamento de até seis meses de pacientes submetidos à cirurgia bariátrica. O estudo foi composto por pacientes que estavam em tratamento no Centro Multidisciplinar de Tratamento da Obesidade (CMTO) Barra da Tijuca, Rio de Janeiro e Centro de Nova Iguaçu. Participaram da pesquisa 101 pacientes divididos em quatro Grupos. Grupo 1 com 40 pacientes obesos pré-cirúrgicos, Grupo 2, 29 (perda de 11) reavaliados póscirurgicamente seis meses depois. Grupo 3 com 20 pacientes, que se distingue do 1 e 2, por passarem por tratamento odontológico profilático e o mesmo grupo tratado, foi avaliado e chamado de grupo 4, com 17 pacientes (perda de 3) reavaliados, seis meses após. A análise de Dados, para realização dos testes, foi utilizado o teste K-S, os dados não são normalmente distribuídos (p < 0,05%). Foi então utilizada a distribuição t de Student para determinação dos intervalos de confiança para a média, o teste de Mann-whitney (significância p > 0,05) mostrou diferença significativa entre os grupos Gr3 e Gr4 no teste salivar. O programa analítico foi o Statistical Package for the Social Sciences (SPSS) versão 16.0 for Windows (NESC/UFRJ). Foram considerados significativos valores numéricos de P 0,05


This study aimed to compare patients who underwent bariatric surgery with and without oral treatment. The methodology used was questionnaires with general data of the patient (anamnesis and clinical examination), questionnaire of self-perception of patient's oral health (OHIP-14), eating habits questionnaire, salivary tests index for dental erosion (BEWE) and periodontal indexes. The results showed that the groups treated by a dentist showed gains as self-perception of oral health (OHIP-14 questionnaire), in improvement of the periodontal problems and confirmed a decrease in pH and an increase in vomiting frequency in post surgical patients. Thus, based on this research findings, it could be concluded that the inclusion of a dentist in the treatment team of patients undergoing bariatric surgery should be encouraged. Morbid obesity has become a public health problem, from the change in dietary habits of the 21st Century. An experimental controlled and non-randomized study, with a follow-up to six months in patients undergoing bariatric surgery was performed. The study consisted of patients who were being treated at the Multidisciplinary Center for Treatment of Obesity (CMTO). The participants were 101 patients divided into four groups. Group 1 with 40 pre-surgical obese patients; Group 2, 29 Patients (loss of 11) post-surgically re-evaluated after 6 months. Group 3 with 20 patients, which distinguishes the 1 and 2 by passing through oral treatment. Group 4 with 17 patients (loss of 3) evaluated six months after.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Tooth Erosion/etiology , Gastroesophageal Reflux/complications , Laryngopharyngeal Reflux/complications , Dentin Sensitivity , Bariatric Surgery/adverse effects
12.
Braz. j. otorhinolaryngol. (Impr.) ; 80(1): 5-10, Jan-Feb/2014. tab, graf
Article in Portuguese | LILACS | ID: lil-704078

ABSTRACT

Introdução: A apneia obstrutiva do sono (AOS) é causada por episódios recorrentes de obstrução total ou parcial da via aérea superior com duração superior a 10 segundos durante o sono. Refluxo faringolaríngeo (RFL) é uma variante da doença do refluxo gastroesofágico que afeta a laringe e a faringe. Objetivos: Avaliar a influência da obesidade na relação entre RFL e AOS em pacientes com SAOS. Materiais e métodos: Estudo observacional transversal retrospectivo. Foram revisados protocolos de atendimento de pacientes com AOS que incluem questionários validados para RFL como Reflux Sympton Index (RSI) e Reflux Finding Score (RSI), nasolaringofibroscopia e polissonografia. Resultados: Cento e cinco pacientes foram divididos em grupo de obesos (39 pacientes) e não obesos (66 pacientes). Na avaliação das médias do RSI o grupo de não obesos foi semelhante entre pacientes com AOS leve (11,96) e moderada (11,43). No grupo de obesos a média do RSI foi de 6,7 em pacientes com AOS leve e de 11,53 em pacientes com AOS moderada a grave (p < 0,05). Discussão: O subgrupo de pacientes com AOS e RFL apresenta vários fatores que promovem a inflamação da via aérea superior. Pacientes com AOS devem ser pesquisados e tratados quanto a RFL, aumentando a qualidade de vida. Conclusão: O RFL e a AOS se correlacionam positivamente em pacientes obesos. .


Introduction: The obstructive sleep apnea (OSA) is caused by recurrent episodes of partial or total obstruction of the upper airway lasting more than 10 seconds during sleep. Laryngopharyngeal reflux (LPR) is a variant of the disease Gastroesophageal Reflux that affects the larynx and pharynx. Objectives: Evaluate the influence of obesity on the relationship between RFL and OSAS in patients with OSA. Materials and methods: An observational retrospective cross. We reviewed care protocol for patients with OSA that includes validated questionnaires for RFL as Sympton Reflux Index (RSI) and Reflux Finding Score (RSI), and polysomnography nasolaringofibroscopia. Results: 105 patients were divided into obese group (39 patients) and non-obese patients (66 patients). In the evaluation of the mean RSI group of non-obese was similar between patients with mild OSA (11.96) and moderate (11.43). In the obese group the mean RSI was 6.7 in patients with mild OSA and 11.53 in patients with moderate to severe OSA (p < 0.05). Discussion: The subgroup of patients with OSA and RFL have several factors that promote inflammation of the upper airway. Patients with OSA should be screened and treated as the RFL increasing the quality of life. Conclusion: The RFL are positively correlated and OSAS in obese patients. .


Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , Laryngopharyngeal Reflux/complications , Obesity/complications , Sleep Apnea, Obstructive/complications , Body Mass Index , Epidemiologic Methods , Laryngopharyngeal Reflux/physiopathology , Obesity/physiopathology , Polysomnography , Sleep Apnea, Obstructive/physiopathology
13.
Braz. j. otorhinolaryngol. (Impr.) ; 79(5): 589-593, Sep-Oct/2013. graf
Article in Portuguese | LILACS | ID: lil-688604

ABSTRACT

Acredita-se que haja uma associação entre síndrome da apneia obstrutiva do sono (SAOS) e refluxo laringofaríngeo (RLF). OBJETIVO: Estudar a prevalência de sintomas/sinais de refluxo em pacientes roncadores com suspeita de SAOS. MÉTODO: Estudo clínico corte transversal de 74 adultos Berlim positivo acompanhados em ambulatório de distúrbios do sono de centro universitário. As variáveis estudadas foram IMC, Epworth, índice de sintomas de refluxo (RSI) e escala de achados endolaríngeos de refluxo (RFS), bem como seus subdomínios que podem traduzir maior inflamação. Correlações entre questionários de sono e escalas de refluxo, bem como seus subdomínios, foram feitas com significância estabelecida em p < 0,05. RESULTADOS: Noventa e oito porcento dos pacientes apresentaram sintomas e sinais sugestivos de RLF, sendo esta prevalência significativamente maior nos obesos (p = 0,002). CONCLUSÃO: A diferença significativa nos sinais inflamatórios sugestivos de RLF entre obesos e não obesos com suspeita de SAOS sugere que a obesidade pode interferir nos achados inflamatórios na faringe e laringe. A altíssima prevalência destes sintomas e sinais de refluxo nos pacientes com suspeita de SAOS demonstra a importância de aprofundar estudos nesta área. .


OBJECTIVE: To study the prevalence of signs and symptoms of reflux in snorers with suspected OSA. METHOD: This cross-sectional study enrolled 74 patients assessed positive for OSA with the Berlin questionnaire. The subjects were followed up at the sleep disorder ward of a university center. Studied variables included the BMI, the Epworth sleepiness scale, the reflux symptom index (RSI), the reflux finding score (RFS), and their subdomains related to increased inflammation. The correlations between sleep questionnaires, reflux scales, and their subdomains were deemed statistically significant when p < 0.05. RESULTS: Ninety-eight percent of the subjects had symptoms and signs suggestive of LPR; prevalence was significantly higher among obese individuals (p = 0.002). CONCLUSION: The significant difference seen in the prevalence of signs of inflammation suggestive of LPR when obese and non-obese subjects with suspected OSA were compared indicates that obesity may affect inflammatory findings of the pharynx and larynx. The high prevalence of symptoms and signs of reflux in patients with suspected OSA calls for more studies on the matter. .


Subject(s)
Adult , Humans , Male , Middle Aged , Young Adult , Laryngopharyngeal Reflux/diagnosis , Sleep Apnea, Obstructive/diagnosis , Snoring/complications , Body Mass Index , Epidemiologic Methods , Laryngopharyngeal Reflux/complications , Polysomnography , Sleep Apnea, Obstructive/complications
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